Hypoxyprobe Tools for Mapping Oxygen Shortage in Tissue
A unique Antibody allows for screening of oxygen supply in tissue and organs. A non-toxic small molecule compound (generic name Pimonidazol x HCl, Pim x HCl) is administered orally or intravenously (through the tail vene). Distribution can be picked up by 1) small animal nuclear magnetic resonance 2) positron emission tomography 3) simple immunohistochemistry. Artimmun Analytik GmbH, in cooperation with Hypoxyprobe and NPI, supplies a sensitive test kit for monitoring areas of oxygen shortage using standard immunohistochemistry.
This Hypoxyprobe(tm) Gemini kit allows for dual screening of oxygen distribution using two non-crossinteracting antibodies. Combine the primary antibodies of this kit with detection antibodies selected according to your experimental setup. View the following reference for more information about dual screening Miriam M Kleiter et al, Int J Radiation Oncology Biol.Phys (2006) Vol 64, 592-602 Order details (Kits refer to 100 mg Pim x HCl)
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